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1

The Global Thymus Network: past, present and future

Yousuke Takahama, Takashi Saito, Hiroshi Kawamoto, Manami Itoi, Richard L. Boyd, Ann Chidgey, Rose Zamoyska, Georg A. Holländer, Graham Anderson, Naomi Taylor, Howard T. Petrie, Janko Nikolich-Žugich

Journal:

Trends in Immunology

Année:

2009

Langue:

english

Fichier:

PDF, 102 KB

english, 2009

2

Co-capping studies reveal CD8/TCR interactions after capping CD8β polypeptides and intracellular associations of CD8 with p56lck

Gek-Eng Kwan Lim, Louise McNeill, Kate Whitley, David L. Becker, Rose Zamoyska

Journal:

European Journal of Immunology

Année:

1998

Langue:

english

Fichier:

PDF, 245 KB

english, 1998

3

Greatly reduced efficiency of both positive and negative selection of thymocytes in CD45 tyrosine phosphatase-deficient mice

P. Joseph Mee, Martin Turner, M. Albert Basson, Patrick S. Costello, Rose Zamoyska, Victor L. J. Tybulewicz

Journal:

European Journal of Immunology

Année:

1999

Langue:

english

Fichier:

PDF, 230 KB

english, 1999

4

Allosuppression: evidence for the involvement of both “noncytotoxic” and cytotoxic T cells

Rose Zamoyska, Herman Waldmann

Journal:

European Journal of Immunology

Année:

1984

Langue:

english

Fichier:

PDF, 785 KB

english, 1984

5

Peripheral tolerance mechanisms prevent the development of autoreactive T cells in chimeras grafted with two minor incompatible thymuses

Rose Zamoyska, Herman Waldmann, Polly Matzinger

Journal:

European Journal of Immunology

Année:

1989

Langue:

english

Fichier:

PDF, 705 KB

english, 1989

6

Anti-CD3-induced cell death in T cell hybridomas: mitochondrial failure and DNA fragmentation are distinct events

Stanislav Vukmanović, Rose Zamoyska

Journal:

European Journal of Immunology

Année:

1991

Langue:

english

Fichier:

PDF, 624 KB

english, 1991

7

Identification of thymocyte precursors in murine fetal liver

Sarah E. Bell, Rose Zamoyska

Journal:

European Journal of Immunology

Année:

1991

Langue:

english

Fichier:

PDF, 725 KB

english, 1991

8

Transgene-encoded human CD2 acts in a dominant negative fashion to modify thymocyte selection signals in mice

Elizabeth Melton, Nitza Sarner, Michaela Torkar, P. Anton van der Merwe, Jennifer Q. Russell, Ralph C. Budd, Clio Mamalaki, Mauro Tolaini, Dimitris Kioussis, Rose Zamoyska

Journal:

European Journal of Immunology

Année:

1996

Langue:

english

Fichier:

PDF, 1.31 MB

english, 1996

9

Signals through CD8 or CD4 can induce commitment to the CD4 lineage in the thymus

Ursula Bommhardt, Michael S. Cole, J. Yun Tso, Rose Zamoyska

Journal:

European Journal of Immunology

Année:

1997

Langue:

english

Fichier:

PDF, 1.48 MB

english, 1997

10

CD8α/α homodimers fail to function as co-receptor for a CD8-dependent TCR

Anne-Marie McNicol, Gavin Bendle, Angelika Holler, Theres Matjeka, Emma Dalton, Lorna Rettig, Rose Zamoyska, Wolfgang Uckert, Shao-An Xue, Hans J. Stauss

Journal:

European Journal of Immunology

Année:

2007

Langue:

english

Fichier:

PDF, 270 KB

english, 2007

11

The influence of mTOR on T helper cell differentiation and dendritic cell function

Robert J. Salmond, Rose Zamoyska

Journal:

European Journal of Immunology

Année:

2011

Langue:

english

Fichier:

PDF, 126 KB

english, 2011

12

Signalling in T-lymphocyte development: integration of signalling pathways is the key

Rose Zamoyska, Matthew Lovatt

Journal:

Current Opinion in Immunology

Année:

2004

Langue:

english

Fichier:

PDF, 139 KB

english, 2004

13

Signalling in T-cell development: is it all location, location, location?

Lisa Miosge, Rose Zamoyska

Journal:

Current Opinion in Immunology

Année:

2007

Langue:

english

Fichier:

PDF, 259 KB

english, 2007

14

The CD4/CD8 lineage decision: integration of signalling pathways

M.Albert Basson, Rose Zamoyska

Journal:

Immunology Today

Année:

2000

Langue:

english

Fichier:

PDF, 234 KB

english, 2000

15

Regulation of peripheral T-cell homeostasis by receptor signalling

Benedict Seddon, Rose Zamoyska

Journal:

Current Opinion in Immunology

Année:

2003

Langue:

english

Fichier:

PDF, 97 KB

english, 2003

16

CD4 and CD8: modulators of T-cell receptor recognition of antigen and of immune responses?

Journal:

Current Opinion in Immunology

Année:

1998

Langue:

english

Fichier:

PDF, 663 KB

english, 1998

17

The influence of the src-family kinases, Lck and Fyn, on T cell differentiation, survival and activation

Rose Zamoyska, Albert Basson, Andrew Filby, Giuseppe Legname, Matthew Lovatt, Benedict Seddon

Journal:

Immunological Reviews

Année:

2003

Langue:

english

Fichier:

PDF, 483 KB

english, 2003

18

LAT Polices T Cell Activation

Rebecca Brownlie, Rose Zamoyska

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 197 KB

english, 2009

19

Age-related variation in immunity in a wild mammal population

Daniel H. Nussey, Kathryn Watt, Jill G. Pilkington, Rose Zamoyska, Tom N. McNeilly

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 267 KB

english, 2012

20

Molecular requirements for lineage commitment in the thymus – antibody-mediated receptor engagements reveal a central role for lck in lineage decisions

M. Albert Basson, Ursula Bommhardt, P. Joe Mee, Victor L. J. Tybulewicz, Rose Zamoyska

Journal:

Immunological Reviews

Année:

1998

Langue:

english

Fichier:

PDF, 7.36 MB

english, 1998

21

T-cell receptor proximal signaling via the Src-family kinases, Lck and Fyn, influences T-cell activation, differentiation, and tolerance

Robert J. Salmond, Andrew Filby, Ihjaaz Qureshi, Stefano Caserta, Rose Zamoyska

Journal:

Immunological Reviews

Année:

2009

Langue:

english

Fichier:

PDF, 820 KB

english, 2009

22

A beginner's guide to major histocompatibility complex function

Matzinger, Polly, Zamoyska, Rose

Journal:

Année:

1982

Fichier:

PDF, 134 KB

1982

23

Self tolerance is H–2-restricted

Matzinger, Polly, Zamoyska, Rose, Waldmann, Herman

Journal:

Année:

1984

Fichier:

PDF, 395 KB

1984

24

Transfection of the CD8 gene enhances T-cell recognition

Dembić, Zlatko, Haas, Werner, Zamoyska, Rose, Parnes, Jane, Steinmetz, Michael, von Boehmer, Harald

Journal:

Année:

1987

Fichier:

PDF, 226 KB

1987

25

Inability of CD8α′polypeptides to associate with p56 lck correlates with impaired function in vitro and lack of expression in vivo

Zamoyska, Rose, Derham, Paula, Gorman, Scott D., von Hoegen, Paul, Bolen, Joseph B., Veillette, André, Parnes, Jane R.

Journal:

Année:

1989

Fichier:

PDF, 464 KB

1989

26

Switching sides: transcriptional control of CD4 thymocyte lineage commitment

Journal:

Nature Immunology

Année:

2005

Langue:

english

Fichier:

PDF, 421 KB

english, 2005

27

Interleukin 7 and T cell receptor signals regulate homeostasis of CD4 memory cells

Seddon, Benedict, Tomlinson, Peter, Zamoyska, Rose

Journal:

Nature Immunology

Année:

2003

Langue:

english

Fichier:

PDF, 1.87 MB

english, 2003

28

Insights into T-cell development from studies using transgenic and knockout mice

M. Albert Basson, Rose Zamoyska

Journal:

Molecular Biotechnology

Année:

2001

Langue:

english

Fichier:

PDF, 137 KB

english, 2001

29

T-Cell Differentiation: Chromatin Remodelling in CD4/CD8 Regulation

Journal:

Current Biology

Année:

2003

Langue:

english

Fichier:

PDF, 255 KB

english, 2003

30

OR.90. Crosstalk between Notch1 and TCR signalling pathways in Th2 differentiation

Anne-Christine Field, Valentino Parravicini, Pete Tomlinson, Rose Zamoyska

Journal:

Clinical Immunology

Année:

2006

Langue:

english

Fichier:

PDF, 40 KB

english, 2006

31

Why Is There so Much CD45 on T Cells?

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 165 KB

english, 2007

32

Memories are made of this: synergy of T cell receptor and cytokine signals in CD4+ central memory cell survival

Stefano Caserta, Rose Zamoyska

Journal:

Trends in Immunology

Année:

2007

Langue:

english

Fichier:

PDF, 299 KB

english, 2007

33

Inducible Expression of a p56Lck Transgene Reveals a Central Role for Lck in the Differentiation of CD4 SP Thymocytes

Giuseppe Legname, Ben Seddon, Matthew Lovatt, Peter Tomlinson, Nitza Sarner, Mauro Tolaini, Keith Williams, Trisha Norton, Dimitris Kioussis, Rose Zamoyska

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 275 KB

english, 2000

34

A Requirement for the Rho-Family GTP Exchange Factor Vav in Positive and Negative Selection of Thymocytes

Martin Turner, P.Joseph Mee, Alice E Walters, Marian E Quinn, Andrew L Mellor, Rose Zamoyska, Victor L.J Tybulewicz

Journal:

Année:

1997

Langue:

english

Fichier:

PDF, 186 KB

english, 1997

35

T cell receptor signalling networks: branched, diversified and bounded

Brownlie, Rebecca J., Zamoyska, Rose

Journal:

Nature Reviews Immunology

Année:

2013

Langue:

english

Fichier:

PDF, 2.01 MB

english, 2013

36

Reconstitution of MHC class I specificity by transfer of the T cell receptor and Lyt-2 genes

Gabert, Jean, Langlet, Claire, Zamoyska, Rose, Parnes, Jane R., Schmitt-Verhulst, Anne-Marie, Malissen, Bernard

Journal:

Année:

1987

Langue:

english

Fichier:

PDF, 1.49 MB

english, 1987

37

The CD8 coreceptor revisited: One chain good, two chains better

Journal:

Année:

1994

Langue:

english

Fichier:

PDF, 1.49 MB

english, 1994

38

Proximity of TCR and its CD8 coreceptor controls sensitivity of T cells

Borger, Jessica G., Zamoyska, Rose, Gakamsky, Dmitry M.

Journal:

Immunology Letters

Année:

2014

Langue:

english

Fichier:

PDF, 1.36 MB

english, 2014

39

The Rho-Family GTP Exchange Factor Vav Is a Critical Transducer of T Cell Receptor Signals to the Calcium, ERK, and NF-κ B Pathways

Patrick S. Costello, Alice E. Walters, P. Joseph Mee, Martin Turner, Lucinda F. Reynolds, Antonella Prisco, Nitza Sarner, Rose Zamoyska and Victor L. J. Tybulewicz

Journal:

Proceedings of the National Academy of Sciences

Année:

1999

Langue:

english

Fichier:

PDF, 1.66 MB

english, 1999

40

Novel Strategy for Microsphere-Mediated DNA Transfection

Borger, Jessica G., Cardenas-Maestre, Juan Manuel, Zamoyska, Rose, Sanchez-Martin, Rosario M.

Journal:

Bioconjugate Chemistry

Année:

2011

Langue:

english

Fichier:

PDF, 2.30 MB

english, 2011

41

The tyrosine phosphatase PTPN22 discriminates weak self peptides from strong agonist TCR signals

Salmond, Robert J, Brownlie, Rebecca J, Morrison, Vicky L, Zamoyska, Rose

Journal:

Nature Immunology

Année:

2014

Langue:

english

Fichier:

PDF, 943 KB

english, 2014

42

Ligand-engaged TCR is triggered by Lck not associated with CD8 coreceptor

Casas, Javier, Brzostek, Joanna, Zarnitsyna, Veronika I., Hong, Jin-sung, Wei, Qianru, Hoerter, John A. H., Fu, Guo, Ampudia, Jeanette, Zamoyska, Rose, Zhu, Cheng, Gascoigne, Nicholas R. J.

Journal:

Nature Communications

Année:

2014

Langue:

english

Fichier:

PDF, 1.44 MB

english, 2014

43

How does the mammalian target of rapamycin (mTOR) influence CD8 T-cell differentiation?

Salmond, Robert J., Zamoyska, Rose

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 572 KB

english, 2010

44

Unprimed T cells are inefficiently stimulated by glycosylphosphatidylinositol-linked H-2K b because of its lipid anchor rather than defects in CD8 binding

Zamoyska, Rose, Ong, Tim, Kwan-Lim, Gek, Tomlinson, Peter, Robinson, Peter J.

Journal:

International Immunology

Année:

1996

Langue:

english

Fichier:

PDF, 2.32 MB

english, 1996

45

Phosphorylation of murine CD8α is not essential for responses of T cell hybridomas to antigen

Williams, Owen, Vukmanovic, Stanislav, Zamoyska, Rose

Journal:

International Immunology

Année:

1991

Langue:

english

Fichier:

PDF, 3.41 MB

english, 1991

46

Is CD8 dependence a true reflection of TCR affinity for antigen?

Kwan-Lim, Gek-Eng, Ong, Tim, Aosai, Fumie, Stauss, Hans, Zamoyska, Rose

Journal:

International Immunology

Année:

1993

Langue:

english

Fichier:

PDF, 914 KB

english, 1993

47

Cellular and humoral immunity in a wild mammal: Variation with age & sex and association with overwinter survival

Watson, Rebecca L., McNeilly, Tom N., Watt, Kathryn A., Pemberton, Josephine M., Pilkington, Jill G., Waterfall, Martin, Hopper, Phoebe R.T., Cooney, Daniel, Zamoyska, Rose, Nussey, Daniel H.

Journal:

Ecology and Evolution

Année:

2016

Langue:

english

Fichier:

PDF, 741 KB

english, 2016

48

Caveolin-1 Influences LFA-1 Redistribution upon TCR Stimulation in CD8 T Cells

Borger, Jessica G., Morrison, Vicky L., Filby, Andrew, Garcia, Celine, Uotila, Liisa M., Simbari, Fabio, Fagerholm, Susanna C., Zamoyska, Rose

Journal:

The Journal of Immunology

Année:

2017

Langue:

english

Fichier:

PDF, 1.81 MB

english, 2017

49

Protein Tyrosine Phosphatase PTPN22 regulates IL-1β dependent Th17 responses by modulating dectin-1 signaling in mice

Purvis, Harriet A, Clarke, Fiona, Jordan, Christine K, Blanco, Cristina Sanchez, Cornish, Georgina H, Dai, Xuezhi, Rawlings, David J, Zamoyska, Rose, Cope, Andrew P

Journal:

European Journal of Immunology

Année:

2017

Langue:

english

Fichier:

PDF, 1.23 MB

english, 2017

50

Resistance to TGFβ suppression and improved anti-tumor responses in CD8+ T cells lacking PTPN22

Brownlie, Rebecca J., Garcia, Celine, Ravasz, Mate, Zehn, Dietmar, Salmond, Robert J., Zamoyska, Rose

Journal:

Nature Communications

Année:

2017

Langue:

english

Fichier:

PDF, 1.18 MB

english, 2017